"Mad crashes into happy and sad bounces off of guilty until they all live in a big smoky heap in my mind." Fourteen-year-old Cameron Galloway of Lexington, Washington, understands that he has schizophreniform disorder and needs to take pills to quiet the voices in his head. But he likes the voices, especially the gentle, encouraging voice of The Girl. Conflicted, he turns to his friend Nina Savage, who is clinically depressed and can relate to his horror of the numbing effects of medication. They make a pact to ditch the pills. At first they feel triumphant, but soon Cameron's untreated mind goes haywire—to disastrous effect.